Well, first up, there is hardly a cartoon or animated show where Jeff Glen Bennett (Petrie) and Rob Paulsen (Spike/Guido etc) do NOT star. There are probably the most sort-after voice over artists on the planet that aren't classed as A-list celebrities. Aria Curzon plays as Corn-Chip Girl in the Disney series Recess and played in the rather sadly rated Santa with Muscles (according to IMDB.com) with Hulk Hogan (the old school Wrestler). Anndi McAfee (of no coincidence that her younger brother Scott McAfee voiced Littlefoot LBT 2-4) voices the blonde Ashley on Disney's Recess as well as a role in Nickelodeon's Hey Arnold (I forget if it's Phoebe or Helga).
Heather Hogan (Ducky 2-4) funnily enough (as with Scott Menville) voiced Colette in the same video game that Menville plays Lloyd in Tales of Symphonia. Littlefoot's Grandpa (Kenneth Mars) has a solid dedicated role as King Triton in Disney's Little Mermaid (from the movies, to the TV series, even down to the Atlantica world in the video game Kingdom Hearts. Also, Mars has also started in a few of the Police Academy movies as well as the detective series Murder She Wrote.
The cast of LBT, most of them have had other roles before coming onto our screens as LBT characters. The only one who seems to chop and change his tone is Littlefoot. The problem stated with Littlefoot's voice is that the boys that get to voice him are normally at the point where their voices start breaking and (with the natural passage of time and puberty) they then become unsuitable to become our loveable longneck. All the others seem to be able to keep their roles.