I've never used netscape or opera (although trying opera has been on my to do list) so I can't give my opinion on that. I have used IE, Firefox, and Chrome on my own computers and have tried Safari (not on any of my computers, i have enough issues running itunes). First off, Safari is the WORST browser ever created. I hate it, and using it is like torture. Back in the IE 6 days thats all I used, but I've been having problems with IE 7 and IE 8. Firefox is a great browser and has seen alot of use by me, but its missing a few features that I really enjoy on Chrome. Right now I use combination of IE 8, Firefox and Chrome, depending on what I need to use. I used to use Firefox the most but I've recently been using Chrome more and more (I'm posting this with Chrome).