Personally for me, I just flat out HATE this adaption to the series...
Why? Well, here's just a couple of reasons on why I dislike it;
1. Lilo is hardly in it. I do know for a fact that she was featured in the anime at some point, but then never seen again. For the most part, she's been replaced by Yuna, yet another blatantly obvious Mary-Sue. <_< Seriously man, it only took her FIVE FREAKING MINUTES to bond with Stitch, while it took Lilo an ENTIRE movie! Not only that, but Yuna was actually able to nearly defeat Stitch with her moves; black belt or not, you can't just be as strong as Stitch and nearly win... Unless you're 627 or Leroy.
2. Some of the characters don't act as they should, case and point, Angel, or experiment number 624 as she's often called. Seriously, she's every freaking female cliche' in the book; she's a freaking gold digger who only loves Stitch if he goes out and buys her expensive crap! I mean, what the heck? Angel never acted that way in the original series! Sure, you could give me the argument that it's just how Japan views the characters, but I honestly don't care... They completely ruined Angel's character for me...
3. They don't even bother to teach you about the Japanese culture throughout the series, unlike that in the original, where you learn all different types of Hawaiian sayings and customs.
Case and point, I really hate this anime.
If you're one of those who likes it just fine, then I really have nothing against you.
This is just my own thoughts on it.