I recently learned about a Chrome browser extension called Ghostery.
It's an extension specifically designed to let you use websites that don't function properly with adblockers turned on (like my Wired example earlier in this thread). Basically, if you use the extension, the website you're on doesn't know you have an adblocker so it functions normally. You, however, can continue blocking ads as normal.
It does a lot of privacy stuff as well, for those of your interested in protecting online privacy a little more.
I don't know if it's 100% effective but it's worked on every site I've tried it on so far.
Check it out!
[EDIT] Cool! With Ghostery running and configured to block "All Advertisers", I can completely disable my other adblocker extension. Ghostery is doing a much better job of working invisibly than my old ad blocker.
If you're having any problem with your adblocker being detected, check out Ghostery. When you tell it to block all ads, it seems to have zero problems with site compatibility so far.

Note that you'll probably still need a good old-fashioned adblocker for Youtube videos and similar stuff like that.